Dramatic surveillance footage shows a cop shooting a blood-covered madman who charged at the officer with a jagged piece of glass inside a Southern California hospital.

Luis Ramirez-Macias, 46, lunged at Simi Valley Police Officer Carly Grice inside Los Robles Hospital in Thousand Oaks, where he was under police guard after allegedly trying to kill his wife that day.

The disturbing footage shows Ramirez-Macias naked and smeared with blood as he moves through the hospital clutching what police said was a makeshift weapon made from a shattered glass vial.

Grice can be seen backing away as Ramirez-Macias advances toward her before she fires a…

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