Of the long list of psychiatric medications Lindsay Clancy was prescribed in the months before she killed her three children in their Massachusetts home in 2023, one drug has come up repeatedly during trial: Seroquel.

In testimony this week, it was revealed that Clancy’s nurse practitioner, Rebecca Jollotta, initially prescribed the non-controlled antipsychotic as an off-label treatment for insomnia — before increasing the dose for mood stabilization.

The disturbing, headline-grabbing case is shining a spotlight on the surprisingly common practice of using the drug, which is FDA-approved for psychiatric disorders but has strong sedating…

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