Do the crossword every day. Exercise 150 minutes per week. Follow the Mediterranean diet.

While for most people these commandments of healthy living lower the risk of developing dementia with advancing age, in some individuals cognitive decline is unrelated to what they do, or fail to do. It is coded in their DNA, tied to a specific genetic mutation — and may well emerge during the prime of life no matter what healthy habits they adopt.

In his new book, “The Vanishing Family: Love, Fate and the Quest to End Dementia,” Robert Kolker chronicles three generations of a family grappling with just such a cruel reality. The author tells their…

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